New Research Links Depo Provera to Meningioma. If You Were Diagnosed After Using This Birth Control, Learn Your Legal Rights and How To Join The Growing Litigation
Depo-Provera was pitched as a simple and effective solution for birth control. “Convenience” was the word most often associated with it. One injection every few months. No daily pill, no invasive device, and no ongoing hassle. Then, years later, a Depo Provera alert came out about brain tumor risks.
For decades, it was marketed as safe, reliable birth control that doctors trusted and one that millions of women have relied upon. That trust is now at the center of a growing legal reckoning.
Across the country, women who used Depo-Provera for extended periods and were later diagnosed with brain tumors are stepping forward. These lawsuits are not isolated. They are building quickly, in numbers large enough to begin forcing real change.
The Yost Legal Group believes the science. We believe the women who are bravely speaking up about their meningioma diagnoses after using Depo-Provera. The link between Depo-Provera use and the development of meningioma is strong. Even the United States Food and Drug Administration (FDA) has formally responded.
The litigation is moving fast and only gaining steam.
If you or a loved one was diagnosed with a brain tumor or meningioma after taking the Depo shot, you may have a case. Call or text the experienced Depo Provera lawyers at The Yost Legal Group. You will receive a free, confidential consultation at 410-659-6800. You may qualify to file a depo provera pfizer lawsuit.
A Brief Refresher on the Depo Provera Lawsuit
Depo-Provera is the brand name for an injectable drug made with medroxyprogesterone acetate (MPA), a synthetic progestogen. It has been widely prescribed as a long-acting contraceptive and used by millions of women, often for years at a time.
In 2024, peer-reviewed research published in The British Medical Journal identified a statistically significant link between prolonged exposure to certain progestogens—including medroxyprogesterone acetate—and an increased risk of intracranial meningioma, a type of brain tumor.
The findings were later peer-reviewed with subsequent analysis by The Journal of the American Medical Association (JAMA).
What followed was not just a scientific concern, but legal action. Women across the country began filing claims alleging that Pfizer, the manufacturer of Depo Provera birth control, failed to adequately warn patients and providers about this serious risk.
Those cases are no longer scattered. They are being consolidated in a Depo Provera MDL. And the size of that litigation is sending a message.
Depo Provera Lawsuits Increasing in Number
As of January 2026, public filings indicate more than 1,700 Depo Provera cases have been filed and centralized in a federal multidistrict proceeding. That number continues to grow.
For women navigating brain tumor diagnoses, that matters. Women who are suffering through no fault of their own now realize that others share their injuries and struggles.
There is no comfort in another’s pain, but there is in acceptance, community, and understanding. It matters to these women that these claims are taken seriously.
Large pharmaceutical companies such as Pfizer are no strangers to lawsuits. When cases multiply this quickly and across jurisdictions, involving the same alleged injury and drug, regulators and manufacturers must take notice.
FDA Approves New Depo Provera Brain Tumor Warning Label
In December 2025, the U.S. Food and Drug Administration approved a new warning label for Depo-Provera. The updated label requires Pfizer to warn that use of the drug may be associated with meningioma, a brain tumor that forms in the membranes surrounding the brain.
This is a major development for users of the injectable contraceptive.
Drug companies and the FDA do not add warning labels casually. They change when evidence reaches a point regulators can no longer ignore. They change when risk information is deemed significant enough that patients and doctors must be told plainly and directly.
And the timing matters. For years, women received Depo Provera injections without any warning about brain tumor potential risk, even as evidence mounted overseas and in the medical literature. Now, only after litigation has grown nationwide, the FDA has stepped in and required stronger language.
There is currently no publicly announced date for when all Depo-Provera packaging with the new warning will be in circulation. As is typical with FDA label changes, the rollout is expected to be gradual. It will occur in waves as manufacturing updates take effect and existing inventory is depleted.
Some clinics may continue administering Depo-Provera packaged under the old label for a period of time.
But the regulatory shift itself is unmistakable. And the warning is clear.
If you used the Depo Provera birth control injection for years, without being warned about brain tumor risks, and were later diagnosed with a meningioma or another serious brain tumor, you need a Depo lawyer. Contact the experienced defective drug attorneys at The Yost Legal Group for a free consultation.
The Yost Legal Group has over 30 years of experience. We help people harmed by negligence. Call or text today at 410-659-6800.
Prescribed Depo Provera? Diagnosed with Brain Tumor?
The FDA’s decision has different implications depending on when a person received their Depo-Provera injections.
Women who start using Depo Provera after the new warning is in place may have trouble joining lawsuits. Once a risk is clearly disclosed, manufacturers often say that patients were warned. They can claim patients knew about the labeled side effects.
But that does not apply to the countless women who used long term Depo Provera before this change.
For decades, Depo-Provera was prescribed without any warning about meningioma risk. Many women got injection after injection, year after year. They trusted that if there were serious long-term dangers, they would have been informed.
There are still tens of thousands (possibly hundreds of thousands) of people who fall into that category. They used Depo Provera before the label change, then were later diagnosed with meningioma after using Depo.
Now, these women are left to deal with surgery, neurological symptoms, life disruption, and unanswered questions.
The growing number of cases and the FDA’s label decision do not close the door on accountability. They open it wider.
Depo Provera Lawsuit Momentum
When people think of success in mass tort litigation (MDL), they often think only of settlements or verdicts. They are, no doubt, important. But real momentum starts way earlier than settlements.
It starts when Depo lawsuit claims grow too numerous for Big Pharma drug corporations to dismiss. It grows when scientific evidence is validated. And it accelerates when regulators act.
The Depo Provera litigation is at that stage. And The Yost Legal Group is here to help you understand your rights and seek the justice you deserve.
Over 1,700 women have already stepped forward to file Depo Provera meningioma lawsuits. We are already representing many of them. The FDA has now required a brain tumor warning for Depo-Provera’s packaging. And the legal process is continuing to move ahead.
For women who have been living with the consequences of a brain tumor diagnosis after Depo-Provera use, this is not just news. It is validation.
Do Not Navigate Brain Tumor Diagnosis Alone—The Yost Legal Group Is Here to Help
Brain tumors, benign or malignant, can be life-altering. Even meningiomas, often labeled “non-cancerous,” can require invasive surgery, cause seizures, affect cognition, and permanently change a person’s life.
People who trusted a prescription drug deserve answers. They deserve transparency. And when warnings come too late, they deserve accountability, compensation, and justice.
The Depo Provera lawsuits are about more than numbers. Women’s health risks need to be taken seriously and disclosed before harm occurs, not after.
So, if your brain tumor diagnosis is connected to Depo Provera use, now is the time to file a lawsuit.
The Yost Legal Group law firm is reviewing Depo Provera meningioma brain tumor cases nationwide. When your health is at stake, there is no time to delay.
If you or a loved one was diagnosed with a brain tumor after using Depo Provera, call us for help. We are reviewing cases nationwide and fighting to hold powerful pharmaceutical companies accountable.
Call or text today at 410-659-6800. Your case evaluation is free, confidential, and focused on your story.
Continue to check our website for Depo Provera lawsuit updates.
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